Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: synthesis of anti-HIV drug DPC 083.
نویسندگان
چکیده
A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 94 شماره
صفحات -
تاریخ انتشار 2012